Safety Profile Overview
Non-selective beta blocker with alpha-1 blocking activity. Cornerstone of heart failure treatment with reduced ejection fraction.
Generic Name
carvedilol
Brand Names
Coreg, Coreg CR
Therapeutic Class
Alpha/Beta Blocker
Manufacturer
GSK
What Pharma Signal Tracks for Carvedilol
- Adverse Events (FAERS) — All FDA Adverse Event Reporting System reports mentioning Carvedilol, including serious outcomes, hospitalizations, and deaths.
- FDA Recalls — Class I, II, and III recalls, market withdrawals, and safety alerts related to Carvedilol products.
- Label Changes — Boxed warning additions, new contraindications, dosing modifications, and safety-related labeling supplements.
- Risk Score — Composite risk score (0–100) combining adverse event rates, recall history, and label severity with explainable breakdown.
- Pharmacovigilance Signals — Proportional Reporting Ratio (PRR) and Reporting Odds Ratio (ROR) analysis detecting disproportionate adverse reactions.
- Trend Analysis — Monthly time series with anomaly detection for emerging safety signals.
Data Disclaimer: Pharma Signal aggregates data from the FDA Adverse Event Reporting System (FAERS) and other public regulatory sources. FAERS reports do not establish causation. Report counts may reflect prescription volume rather than relative safety. Always consult healthcare professionals for medical decisions.
Get Carvedilol Safety Data via API
One API call returns adverse events, risk scores, recalls, and pharmacovigilance signals for Carvedilol.
curl "https://api.pharma-signal.com/drug/safety/carvedilol" \ -H "X-API-Key: your_key" # Returns risk score, adverse event counts, # serious/death rates, recalls, and signals
Related Safety Intelligence
Pharma Signal provides comparative analysis across therapeutic classes. Compare Carvedilol against other Alpha/Beta Blocker drugs, or explore the full manufacturer portfolio for GSK.
- Head-to-head comparison — Compare up to 5 drugs side by side on all safety metrics.
- Therapeutic class benchmarking — See how Carvedilol ranks within Alpha/Beta Blocker on serious event rates.
- Company portfolio risk — View all drugs from GSK with aggregate risk exposure.
- AI analyst briefs — Get a natural-language safety assessment combining all data sources.