Doxycycline Safety Profile & Adverse Events

Safety Profile Overview

Tetracycline antibiotic for infections, acne, and malaria prophylaxis. Photosensitivity and esophageal ulceration are notable adverse effects.

Generic Name

doxycycline

Brand Names

Vibramycin, Doryx

Therapeutic Class

Tetracycline Antibiotic

Manufacturer

Various

What Pharma Signal Tracks for Doxycycline

Adverse Events (FAERS) — All FDA Adverse Event Reporting System reports mentioning Doxycycline, including serious outcomes, hospitalizations, and deaths.
FDA Recalls — Class I, II, and III recalls, market withdrawals, and safety alerts related to Doxycycline products.
Label Changes — Boxed warning additions, new contraindications, dosing modifications, and safety-related labeling supplements.
Risk Score — Composite risk score (0–100) combining adverse event rates, recall history, and label severity with explainable breakdown.
Pharmacovigilance Signals — Proportional Reporting Ratio (PRR) and Reporting Odds Ratio (ROR) analysis detecting disproportionate adverse reactions.
Trend Analysis — Monthly time series with anomaly detection for emerging safety signals.

Data Disclaimer: Pharma Signal aggregates data from the FDA Adverse Event Reporting System (FAERS) and other public regulatory sources. FAERS reports do not establish causation. Report counts may reflect prescription volume rather than relative safety. Always consult healthcare professionals for medical decisions.

Get Doxycycline Safety Data via API

One API call returns adverse events, risk scores, recalls, and pharmacovigilance signals for Doxycycline.

curl "https://api.pharma-signal.com/drug/safety/doxycycline" \
  -H "X-API-Key: your_key"

# Returns risk score, adverse event counts,
# serious/death rates, recalls, and signals

Try the API API Reference

Related Safety Intelligence

Pharma Signal provides comparative analysis across therapeutic classes. Compare Doxycycline against other Tetracycline Antibiotic drugs, or explore the full manufacturer portfolio for Various.

Head-to-head comparison — Compare up to 5 drugs side by side on all safety metrics.
Therapeutic class benchmarking — See how Doxycycline ranks within Tetracycline Antibiotic on serious event rates.
Company portfolio risk — View all drugs from Various with aggregate risk exposure.
AI analyst briefs — Get a natural-language safety assessment combining all data sources.