Safety Profile Overview
Non-selective NSAID for pain and inflammation. FDA strengthened cardiovascular risk warnings in 2015. GI and renal effects are actively monitored.
Generic Name
ibuprofen
Brand Names
Advil, Motrin
Therapeutic Class
NSAID
Manufacturer
Various
What Pharma Signal Tracks for Ibuprofen
- Adverse Events (FAERS) — All FDA Adverse Event Reporting System reports mentioning Ibuprofen, including serious outcomes, hospitalizations, and deaths.
- FDA Recalls — Class I, II, and III recalls, market withdrawals, and safety alerts related to Ibuprofen products.
- Label Changes — Boxed warning additions, new contraindications, dosing modifications, and safety-related labeling supplements.
- Risk Score — Composite risk score (0–100) combining adverse event rates, recall history, and label severity with explainable breakdown.
- Pharmacovigilance Signals — Proportional Reporting Ratio (PRR) and Reporting Odds Ratio (ROR) analysis detecting disproportionate adverse reactions.
- Trend Analysis — Monthly time series with anomaly detection for emerging safety signals.
Data Disclaimer: Pharma Signal aggregates data from the FDA Adverse Event Reporting System (FAERS) and other public regulatory sources. FAERS reports do not establish causation. Report counts may reflect prescription volume rather than relative safety. Always consult healthcare professionals for medical decisions.
Get Ibuprofen Safety Data via API
One API call returns adverse events, risk scores, recalls, and pharmacovigilance signals for Ibuprofen.
curl "https://api.pharma-signal.com/drug/safety/ibuprofen" \ -H "X-API-Key: your_key" # Returns risk score, adverse event counts, # serious/death rates, recalls, and signals
Related Safety Intelligence
Pharma Signal provides comparative analysis across therapeutic classes. Compare Ibuprofen against other NSAID drugs, or explore the full manufacturer portfolio for Various.
- Head-to-head comparison — Compare up to 5 drugs side by side on all safety metrics.
- Therapeutic class benchmarking — See how Ibuprofen ranks within NSAID on serious event rates.
- Company portfolio risk — View all drugs from Various with aggregate risk exposure.
- AI analyst briefs — Get a natural-language safety assessment combining all data sources.