Safety Profile Overview
S-isomer of omeprazole for GERD and erosive esophagitis. Subject of significant litigation regarding kidney damage claims.
Generic Name
esomeprazole
Brand Names
Nexium
Therapeutic Class
Proton Pump Inhibitor
Manufacturer
AstraZeneca
What Pharma Signal Tracks for Nexium
- Adverse Events (FAERS) — All FDA Adverse Event Reporting System reports mentioning Nexium, including serious outcomes, hospitalizations, and deaths.
- FDA Recalls — Class I, II, and III recalls, market withdrawals, and safety alerts related to Nexium products.
- Label Changes — Boxed warning additions, new contraindications, dosing modifications, and safety-related labeling supplements.
- Risk Score — Composite risk score (0–100) combining adverse event rates, recall history, and label severity with explainable breakdown.
- Pharmacovigilance Signals — Proportional Reporting Ratio (PRR) and Reporting Odds Ratio (ROR) analysis detecting disproportionate adverse reactions.
- Trend Analysis — Monthly time series with anomaly detection for emerging safety signals.
Data Disclaimer: Pharma Signal aggregates data from the FDA Adverse Event Reporting System (FAERS) and other public regulatory sources. FAERS reports do not establish causation. Report counts may reflect prescription volume rather than relative safety. Always consult healthcare professionals for medical decisions.
Get Nexium Safety Data via API
One API call returns adverse events, risk scores, recalls, and pharmacovigilance signals for Nexium.
curl "https://api.pharma-signal.com/drug/safety/nexium" \ -H "X-API-Key: your_key" # Returns risk score, adverse event counts, # serious/death rates, recalls, and signals
Related Safety Intelligence
Pharma Signal provides comparative analysis across therapeutic classes. Compare Nexium against other Proton Pump Inhibitor drugs, or explore the full manufacturer portfolio for AstraZeneca.
- Head-to-head comparison — Compare up to 5 drugs side by side on all safety metrics.
- Therapeutic class benchmarking — See how Nexium ranks within Proton Pump Inhibitor on serious event rates.
- Company portfolio risk — View all drugs from AstraZeneca with aggregate risk exposure.
- AI analyst briefs — Get a natural-language safety assessment combining all data sources.